Abstract: Extraction of the Chromo-cor and saccharides from Rhodiola rosea with different ethanol concentrations as infusions was studied in this paper. Different compounds were assayed with spectrophotometeric method. Results of the study showed that the higher amount of the Chromo-cor content (1.086%) can be extracted from Rhodiola rosea about 24 hours infusion with 50% ethanol and it is considered to be the optimum conditions for the extractions of Chromo-cor. The water extract of the residue infused by 85% ethanol is the optimum one for the extraction of saccharide from Rhodiola rosea and the calculated amount is 1. 086%.The bacteriostatic activities of the different compounds from medicinal plant Rhodiola rosea were also further studied in this experiment. The results showed: the antimicrobial activity of Chromo-cor from Rhodiola rosea on Staphylococcus aureus was the highest among the several bacteria used for the study (the diameter of the antimicrobial circle was 21.25 mm). It alsoshows weak inhibitory effect to E.coli; while the saccharide from the Rhodiola rosea does not show any antimicrobial activity to all bacteria used in this study.

Key words: extraction, Rhodiola rosea, chromo-cor, saccharide