Study on Anti-tumor Effects of Flavonoids Extracted from Sweet Potato Leaf,Stalk and Stem

Abstract

Abstract: The antitumor effects of FSPV were studied in this paper.By using MTT assay and dye exclusion method,the inhibitory effects on 4 tumor cell lines in vitro of FSPV were studied.Cyclophosphamide was the positive control and saline the negative control.S180-bearing mice were used as animal model.The changes of tumor weight in vitro were investigated when FSPV were used.Results:The growth of 4 tumor cells is inhibited by FSPV significantly in dose-dependent manner.Especially the inhibitory effect on the HL-60 is specific up to 70.95%.The antitumor effect of FSPV on the S180 bearing mice is significant.The inhibitory rate is highest when the dose is 400mg/kg bw.Conclusion:FSPV have the antitumor effects on the 4 tumor cell lines and S180-bearing mice.

Key words: sweet potato leaf,stalk and stem, flavonoids, anti-tumor effect, MTT assay

LUO Li-Ping, Gao-Yin-Yu, Hong-Xue-E, Xia-Dong-Hua, Chen-Cai-Shui. Study on Anti-tumor Effects of Flavonoids Extracted from Sweet Potato Leaf,Stalk and Stem[J]. FOOD SCIENCE, 2006, 27(8): 248-250.

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Study on Anti-tumor Effects of Flavonoids Extracted from Sweet Potato Leaf,Stalk and Stem

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