Functions of Cinnamic Acid Derivatives on DNA Damage Induced by Phen-Cu-VC System

Abstract

Abstract: Objective: To understand the protection mechanism of cinnamic acid derivatives to the damage of DNA. Methods: The protection potency of cinnamic acid derivatives to the damage of DNA in the Phen-CuSO4-VC system has been investigated at the ribodesose level with both ultraviolet spectrophotometric method and the TBA reaction, for reference to the effects of Mannitol. Results: Cinnamic acid derivatives do have the protective function to the damage of DNA caused by ·OH.

Key words: derivative of cinnamic acid, hydroxyl radicals, DNA damage

LIU Jin, ZHANG Li-Wei. Functions of Cinnamic Acid Derivatives on DNA Damage Induced by Phen-Cu-VC System[J]. FOOD SCIENCE, 2006, 27(9): 49-51.

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Functions of Cinnamic Acid Derivatives on DNA Damage Induced by Phen-Cu-VC System

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