Abstract: To observe the effects of barley green on serum lipid and malonyldialdehede (MDA), superoxide dismutase (SOD), endothelin-1(ET-1) and nitric oxide (NO). Thirty two rats were fed high fat diet to result in hyperlipidemia models. Then they were randomly divided into blank group(8NC), model group (8HF), BG-L group (treated by low dose barley green) and BG-H group (treated by high dose barley green). Changes of above laboratory indexes were observed. The level of serum total cholesterol (TC), low-density lipoprotein (LDL), MDA and ET-1 of the groups given medicine was lower than that of the model group, while the level of serum high-density lipoprotein (HDL), SOD and NO of the groups given medicine was higher than that of the model. According to the results, barley green can modulate lipid metabolism, resist lipid peroxidation, improve vascular endothelium and prevent atherosclerosis.

Key words: hyperlipidemia, malonylolialdehede(MDA), superoxide dismutase(SOD), endothelin-1(ET-1), nitric oxide (NO)