Investigation on Solvent Technology Prior Supercritical CO2 Extraction and Crystallization of Andrographolide

Abstract

Abstract: Extraction of Andrographis paniculata (Burm.f.) Nees (purity of andrographolide 30%) was investigated for the sorts of solvent, ratio of liquid to solid, extraction temperature, extraction hours and extraction times in technology. The results showed that the ethyl acetone is the optimal solvent with the technology parameters as: ratio of liquid to solid 6:1, extraction temperature50℃, extraction time 3 hours and extraction 3 times. The extract of Andrographis paniculata(Burm.f.) Nees with more than 45% purity of andrographolide and more than 85% extraction ratio can be achieved.

Key words: supercritical CO2, extraction and crystallization, andrographolide, pretreatment, technology

ZHANG Wen-Cheng, PAN Jian, XIE Hui-Ming. Investigation on Solvent Technology Prior Supercritical CO2 Extraction and Crystallization of Andrographolide[J]. FOOD SCIENCE, 2007, 28(2): 130-133.

[1]	SUN Zongbao, Wang Tianzhen, Zou Xiaobo, LIU Yuan, Liang Liming, LI Junkui, Liu Xiaoyu. Discrimination between Raw and Restructured Beef Steak Using Hyperspectral and Ultrasound Imaging [J]. FOOD SCIENCE, 2021, 42(8): 257-263.
[2]	WANG Yue, SHAO Lin, LI Qianxue, YI Le, QU Han, WANG Hongli, SHEN Minghao. Aptamer Combined with Quantum Dot for Simultaneous Detection of Staphylococcus aureus and Escherichia coli O157:H7 [J]. FOOD SCIENCE, 2021, 42(8): 305-312.
[3]	ZHAO Honglei, CHANG Jingyao, CHEN Jiaxin, WANG Hao, LIU Hui, KONG Baohua, LIU Qian. Novel Strategies for Reducing Phosphates in Emulsified Meat Products: A Review of Phosphate Replacers and New Processing Technologies [J]. FOOD SCIENCE, 2021, 42(7): 329-335.
[4]	ZHOU Yunling, WEI Na, HAO Xiaoxiu, WANG Zaiying, LI Yuhan. Progress in Application of Intelligent Packaging Technologies in Food Supply Chain [J]. FOOD SCIENCE, 2021, 42(7): 336-344.
[5]	TIAN Jingsheng, LI Dongdong, ZHAO Lingyu, GAO Wenhui. Preparation and Application of Molecularly Imprinted Electrochemical Sensor for Rapid Detection of Quinoxaline Drug Residues [J]. FOOD SCIENCE, 2021, 42(6): 316-324.
[6]	LI Mingjuan, ZHANG Yayuan, YOU Xiangrong, WANG Ying, ZHOU Kui, WEI Ping, WEI Linyan. Effects of Different Drying Technologies on the Quality Characteristics and Microstructure of Walnut Meal Protein Powder [J]. FOOD SCIENCE, 2021, 42(5): 92-98.
[7]	XU Xiaoxuan, SU Xiaona, TAN Shu, ZHONG Cuili, ZENG Daoping, ZHANG Yan, XU Zhenlin, WANG Xu, YANG Jinyi. Determination of Amantadine and Chloramphenicol Residues in Poultry Meat by Indirect Competitive Chemiluminescence Enzyme-Linked Immunosorbent Assay [J]. FOOD SCIENCE, 2021, 42(4): 305-312.
[8]	WU Youxue, WU Meijiao, TIAN Yachen, WANG Zheng, GUO Liang, LIU Cheng, FANG Shuiqin, LIU Qing. Progress in the Development of Salmonella Biosensors [J]. FOOD SCIENCE, 2021, 42(3): 339-345.
[9]	WANG Dandan, LI Li, YANG Yange, LIU Mingchang, WANG Hongyue, WU Shuqing, YUAN Fei, WU Yajun. Establishment of a Rapid Detection System for Cronobacter spp. [J]. FOOD SCIENCE, 2021, 42(16): 286-292.
[10]	LI Ruiwen, SUN Xiaorong, LIU Cuiling, GUO Zehan, TIAN Mi. Rapid Detection of Polar Components of Used Frying Oils by Raman Spectroscopy [J]. FOOD SCIENCE, 2021, 42(16): 328-332.
[11]	XU Hongwen, XU Hua, ZHU Yu, YE Yongli, SUN Jiadi, SUN Xiulan, ZHANG Xiaojuan. Application of Magnetic Solid-Phase Extraction in the Analysis of Mycotoxins in Foods: A Literature Review [J]. FOOD SCIENCE, 2021, 42(11): 261-270.
[12]	HU Xiaolong, YU Miao, CAO Zhenhua, WANG Kangli, TIAN Ruijie, HAN Suna, LI Hua, LI Jianmin, ZENG Tian, LI Hong. Spatial Heterogeneity of Prokaryotic Microbial Community Diversity in Pit Mud from Degraded Cellar for the Production of Strong-flavor Baijiu Revealed by High Throughput Sequencing [J]. FOOD SCIENCE, 2021, 42(10): 86-93.
[13]	GUO Li, DU Zhenghua, YAO Lihong, CHEN Xiaobing, ZHANG Yi, LIN Zhi, GUO Yaling, CHEN Mingjie. Chemical Characterization of the Aroma of Tieguanyin Oolong Tea and Black Tea [J]. FOOD SCIENCE, 2021, 42(10): 255-261.
[14]	ZHANG Zhihua, ZHONG Shurui, PENG Fei, ZENG Yingjie, ZONG Minhua, LOU Wenyong. Progress in Microcapsule Wall Materials and Preparation Techniques [J]. FOOD SCIENCE, 2020, 41(9): 246-253.
[15]	ZHANG Huanhuan, GAO Feihu, HUANG Taocui, ZENG Zhihong, ZHANG Ling, ZHANG Xuemei, LI Xue, LIANG Yexing. Effects of Pretreatments on Lipid Concomitants Content in Cold Pressed Canola Oil [J]. FOOD SCIENCE, 2020, 41(8): 57-61.

Investigation on Solvent Technology Prior Supercritical CO2 Extraction and Crystallization of Andrographolide

RichHTML

PDF (PC)

Knowledge

Abstract

Cite this article

share this article

References

Related Articles 15

Recommended Articles

Metrics

Comments