Abstract: The artificial neural network (ANN )model for Salidroside microcapsules was optimized by using genetic algorithm (GA) in the light of establishing fitness function, selecting coding method and determining genetic parameters. The highest performance, 14% greater than the biggest in experiments, is obtained when the ratio of alginate weight to Salidroside weight is 2, alginate concentration 3%, chitosan concentration 0.5%, calcium chloride concentration 1% and pH value 6.35. It is a practical method to optimize the ANN model by using GA.

Key words: genetic algorithm(GA), artificial neural network(ANN), microcapsules, optimization