Study on Fuzhuan Tea Extracts Activity with FXR Model by High-Throughput Screening

FOOD SCIENCE ›› 2007, Vol. 28 ›› Issue (5): 331-334.

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Study on Fuzhuan Tea Extracts Activity with FXR Model by High-Throughput Screening

FU Dong-He, LIU Zhong-Hua, HUANG Jian-An, CHEN Jin-Hua, CAI Zheng-An, ZHAO Shu-Juan

1.Key Laboratory of Tea Science,Ministry of Education,Changsha 410128,China; 2.College of Horticulture and Gardens,Hunan Agricultural University,Changsha 410128,China

Online:2007-05-15 Published:2011-12-31

Abstract

Abstract: The infusions of Fuzhuan Tea were extracted by chloroform,ethyl acetate,l-butanol respectively and the tea residues were extracted by ethanol.The samples were used to test their functions in adjusting fat metabolism and hyperlipirmia by Fuzhuan Tea extracts with the FXR models of High-Throughput Screening.The results showed that all the samples of Fuzhuan Tea can restrain FXR models.Ethyl acetate extraction and EGCG and ECG can activate FXR models.Hence Fuzhuan Tea was effective in adjusting fat metabolism and hyperlipidemia.More active components need to be separated later.

Key words: Fuzhuan Tea, FXR(farnesoid X receptor), high-throughput screening

FU Dong-He, LIU Zhong-Hua, HUANG Jian-An, CHEN Jin-Hua, CAI Zheng-An, ZHAO Shu-Juan. Study on Fuzhuan Tea Extracts Activity with FXR Model by High-Throughput Screening[J]. FOOD SCIENCE, 2007, 28(5): 331-334.

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Study on Fuzhuan Tea Extracts Activity with FXR Model by High-Throughput Screening

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