FOOD SCIENCE ›› 2008, Vol. 29 ›› Issue (11): 692-695.

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Research Progress of Physiological Functions of L-malate

 WU  Jun-Lin, WU  Qing-Ping, ZHANG  Ju-Mei   

  1. Guangdong Provincial Key Laboratory of Microbial Culture Collection and Application,Guangdong Institute of Microbiology,Guangzhou 510070,China
  • Online:2008-11-15 Published:2011-12-08

Abstract: L-malate,an important organic acid in the process of metabolism,plays an important role in generating mitochondria ATP.Moreover,L-malate is a component of malate-aspartate shuttle and is of importance in transporting NADH from cytosol to mitochondria for energy production.Therefore,L-malate is endowed with many physiological functions such as enhancing capacity of excises,anti-fatigue,protecting heart,increasing metabolism of carboxylates,improving respiration of mitochondria,increasing activity of calcium and reducing toxicity of anti-cancer medicament.

Key words: L-malate, malate-aspartate shuttle, physiological function