FOOD SCIENCE ›› 2011, Vol. 32 ›› Issue (23): 312-316.doi: 10.7506/spkx1002-6630-201123063

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Research Progress in Mammalian Small Intestinal Lactoferrin Receptors and Functions

MU Li,PANG Guang-chang*   

  1. (Tianjin Key Laboratory of Food and Biotechnology, College of Biotechnology and Food Science, Tianjin University of Commerce, Tianjin 300134, China)
  • Online:2011-12-15 Published:2011-12-21

Abstract: Lactoferrin is a kind of iron-binding glycoprotein with various physiological functions in mammals. Multiple biological activities of lactoferrin depend on its target cells and the presence of specific receptor on its surface. In this paper, the structural characteristics and physiological functions of mammalian lactoferrin receptors are reviewed. Meanwhile, the specific properties of human and mouse small intestinal lactoferrin receptors and their functions, such as facilitating intestinal iron absorption and modulating immune functions are discussed as well.

Key words: lactoferrin, small intestinal lactoferrin receptor, physiological function

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