FOOD SCIENCE ›› 2008, Vol. 29 ›› Issue (4): 114-116.

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Study on Inhibitive Effect of Chitooligosaccharides on Intestinal Causative Microorganism

 CAO  Wei-Qiang, WANG  Jing, SHE  Yong-Xin, ZHAO  Hai-Tian, ZHANG  Ying-Chun, YANG  Xin, ZHANG  Hua   

  1. 1. Institute of Quality Standard and Testing Technology of Agricultral Product, The Chinese Academy of Agricultural Sciences;2. Huizhou Exit-Entry Inspection and Quarantine Bureau; 3. College of Food Science and Genetic Engineering, Harbin Institute of Technology
  • Online:2008-04-15 Published:2011-08-24

Abstract: Chitooligosaccharides were prepared by hydrogen peroxide method, with Q TRAP LC/MS/MS System to determine chitooligosaccharides’ average molecular weight and on the inhibitive effects of chitooligosaccharides on four species intestinal causative microorganism were studied. The inhibitive function is obvious compared with the blank. The results showed that the lowest concentration of chitooligosaccharides inhibiting Esaherichiacoli and Staphylococcusaureus is 0.3%, and the lowest concentration of chitooligosaccharides inhibiting S.paratyphi A and Shigella-sonnei is 0.1%. With the increasing of concentration of chitooligosaccharides, the inhibitive function is enhanced. The results showed that the chitooligosaccharides has good inhibitive effect on intestinal causative microorganism.

Key words: chitooligosaccharides, intestinal causat ive microorganism, antimicrobial activity