Study on Production Technology of Riboflavin Sodium Phosphate

Abstract

Abstract: Effects of riboflavin-phosphorus oxychloride-water ratio,phosphorylation reaction time,and reaction temperature on preparation of riboflavin sodium phosphate were investigated. The results showed that reaction product of riboflavin and 4-times moles of phosphorus oxychloride reacting for 2 h at about 35 ℃ in the mixture of pyridine and acetonitrile as a solvent is hydrolyzed and then neutralized with aqueous sodium hydroxide solution,and then more than 75% riboflavin sodium phosphate is obtained.

Key words: riboflavin sodium phosphate, riboflavin, phosphorus oxychloride, production

SUN Wen-Jing, WEI Zhuan, YU Si-Lian, ZHOU Qiang, HUANG Da-Ming. Study on Production Technology of Riboflavin Sodium Phosphate[J]. FOOD SCIENCE, 2008, 29(8): 188-190 https://doi.org/

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Study on Production Technology of Riboflavin Sodium Phosphate

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