FOOD SCIENCE ›› 2008, Vol. 29 ›› Issue (8): 636-639.

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Research Progress on Fermentation Prcduction of 2-Keto-D-gluconic Acid

 WEI  Zhuan, YU  Si-Lian, SUN  Wen-Jing, ZHOU  Qiang, LI  Zhong-Bing   

  1. 1.Department of Pharmaceutical,Hebei Chemical and Pharmaceutical College,Shijiazhuang 050026,China;2.Parchn Sodium Isovitamin C Co. Ltd.,Dexing 334221,China;3.College of Food and Biological Engineering,Jiangsu University,Zhenjiang 212013,China
  • Online:2008-08-15 Published:2011-08-26

Abstract: 2-Keto-D-gluconic acid(2KGA),usually prepared by fermentative oxidation of D-glucose,is the precursor used in the manufacture of sodium erythorbate or erythorbic acid as a food antioxidant. The paper summarizes the biosynthesis pathway of 2KGA,breeding of 2KGA producing strains,fermentation conditions of the strains producing 2KGA,technology of 2KGA fermentation,isolation and purification of the fermentation product,the main problems and corresponding solutions of the domestic 2KGA fermentation production.

Key words: 2-keto-D-gluconic acid, fermentation, sodium erythorbate, erythorbic acid