Antioxidant Effects of Polysiphonia urceolata Extract on Mice

doi:10.7506/spkx1002-6630-200901061

FOOD SCIENCE ›› 2009, Vol. 30 ›› Issue (1): 255-257.doi: 10.7506/spkx1002-6630-200901061

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Antioxidant Effects of Polysiphonia urceolata Extract on Mice

ZHANG Ting1，LIU Cheng-yin2，LIU Quan-wen3,*，XING Guo-xiu3，QIAO Qing-an3

(1.School of Life Sciences, Ludong University Yantai 264025, China；2.The No.1 Middle School of Qixia, Qixia 265300,
China ；3.School of Chemistry and Materials Science, Ludong University Yantai 264025, China)

Received:2007-12-07 Revised:2008-04-13 Online:2009-01-01 Published:2010-12-29
Contact: LIU Quan-wen3 E-mail:qwliu2001@yahoo.com.cn

Abstract

Abstract:

The total content of bromophenols in red alga Polysiphonia urceolata extract (PUE) was detected by FD method. The antioxidant effects of PUE were detected on mice. The oxidative DNA damage of peripheral lymphocytes induced by H2O2 was analyzed by SCGE. The concentrations of superoxide dismutase (SOD) and malonyldialehyde (MDA) in plasma were detected with test kit. The results showed that the concentration of total phenols in the PUE is proved to be 68.54 % and the PUE shows low toxicity with its LD50 more than 3160 mg/ kg. There is a significant decreasing tendency of the oxidative DNA damage of peripheral lymphocytes in the 40 mg/ kg bw dosage group induced by 10 μmol/ L H2O2. The levels of MDA in all dosage groups are less than that in the control group. In conclusion, the PUE has some anti-lipid peroxidation activity.

Key words: Polysiphonia urceolata, bromophenols, DNA damage, SOD, MDA

CLC Number:

Q949.21

ZHANG Ting1，LIU Cheng-yin2，LIU Quan-wen3,*，XING Guo-xiu3，QIAO Qing-an3. Antioxidant Effects of Polysiphonia urceolata Extract on Mice[J]. FOOD SCIENCE, 2009, 30(1): 255-257.

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Antioxidant Effects of Polysiphonia urceolata Extract on Mice

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