FOOD SCIENCE ›› 2012, Vol. 33 ›› Issue (1): 262-266.

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Research Progress in Bovine Casein Glycomacropeptide for the Improvement of Inflammatory Bowel Disease

  

  • Received:2011-07-21 Revised:2011-12-13 Online:2012-01-15 Published:2012-01-12

Abstract: Casein glycomacropeptide (CGMP) is mainly a class of peptides bearing carbohydrate chains derived from the hydrolysis of κ-casein by tenet. Because CGMP has many physiological functions and unique nutritional properties, it can be widely used in the fields of functional food and medicine. CGMP has been reported to have anti-inflammatory activity such as improvement and immunotherapy on inflammatory bowel disease (IBD). In this paper, the sources, structural characteristics and current research status of CGMP are outlined. Recent research advances in the regulatory, improving and therapeutic effects of CGMP on IBD are reviewed. Moreover, the future development prospects of CGMP are also proposed.

Key words: casein glycomacropeptide (CGMP), inflammatory bowel disease (IBD), immunoregulation, intestinal flora

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