FOOD SCIENCE ›› 2013, Vol. 34 ›› Issue (22): 143-149.

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Determination of 15 perfluorinated compounds in Chinese spirit by dispersive solidphase extraction and HPLC-MS/MS detection

  

  • Received:2013-05-26 Revised:2013-10-15 Online:2013-11-25 Published:2013-12-05

Abstract:

A rapid dispersive solidphase extraction and HPLC-MS/MS detection method was developed for the determination of 15 perfluorinated compounds in Chinese spirit. 1.0 mL sample was extracted by 50 mg PSA dispersive solidphase extraction and eluted with 50 mmol/L triethylamine-methanol solution. Then the extract was further detected by HPLC-MS/MS. Analysis was performed by electrospray ionization in negative mode with multiple reaction monitoring(MRM) using internal standard method for quantitative determination. Good linearities were established for the 15 PFCs in the range from 0.1μg/L to 20.0μg/L. The limits of detection were between 0.03 and 0.15μg/L, while the limits of quantitation were ranged from 0.09 to 0.45μg/L. The average recoveries of 15 PFCs were between 83.8% and 119% in spiking levels of 0.5, 1.0 , 2.0and 5.0μg/L.

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