Experimental Study on Hypolipidemic Effect of Water Decoction of Chickpea Seeds in Rats

doi:10.7506/spkx1002-6630-201001054

FOOD SCIENCE ›› 2010, Vol. 31 ›› Issue (1): 232-234.doi: 10.7506/spkx1002-6630-201001054

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Experimental Study on Hypolipidemic Effect of Water Decoction of Chickpea Seeds in Rats

TIAN Chun-yuan1，ZHOU Xiu-jia2

(1. School of Life Science and Technology, Xiaogan University, Xiaogan 432000, China；2. College of Traditional Chinese Materia
Medica, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China)

Received:2009-01-08 Online:2010-01-01 Published:2014-05-19
Contact: TIAN Chun-yuan1 E-mail:hbtcy@yahoo.com.cn

Abstract

Abstract:

SD male rats were used as experimental animals to investigate whether water decoction of chickpea seeds (WDCS) has hypolipidemic effect. Seventy-two rats were randomly divided into 6 groups of 12 rats each. Rats fed normal diet were served as normal control group and all other groups were fed high fat diet over the whole experimental period. Blood lipid level in rats was assayed after 10 d of high fat diet feeding and 4 weeks and 6 weeks of continuous WDCS administration by gavage. Results showed that WDCS resulted in a decrease in rat serum TC, LDL-C and TG and an increase in HDL-C and APO AI and more significant changes in these blood lipid parameters were observed in high dose administered rats. Therefore, WDCS has a good regulatory effect on blood lipid level in hyperlipidemic rats.

Key words: chickpea, water decoction of chickpea seed(WDCS), hyperlipidemia, hypolipidemic effect

CLC Number:

R286.26

TIAN Chun-yuan1，ZHOU Xiu-jia2. Experimental Study on Hypolipidemic Effect of Water Decoction of Chickpea Seeds in Rats[J]. FOOD SCIENCE, 2010, 31(1): 232-234.

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Experimental Study on Hypolipidemic Effect of Water Decoction of Chickpea Seeds in Rats

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