FOOD SCIENCE ›› 2011, Vol. 32 ›› Issue (3 ): 117-120.doi: 10.7506/spkx1002-6630-201103028

• Basic Research • Previous Articles     Next Articles

Effect of Irradiation on Physico-chemical Properties of Hyaluronic Acid

ZOU Zhao-hui，WANG Qiang，WANG Zhi-dong，DENG Gang-qiao，LI Shu-rong，GAO Mei-xu，CHEN Yong-hao，FAN Bei，LI Qing-peng，ZHAO Hong-wei   

  1. 1.中国农业科学院农产品加工研究所，农业部农产品加工与质量控制重点开放实验室，北京 100193；
    2.湖南农业科学院原子能农业应用研究所，湖南长沙 410125
  • Received:2010-06-07 Revised:2011-01-08 Online:2011-02-15 Published:2011-01-13

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Abstract: The 60Co-γ irradiation treatment on 0.5 g/100mL hyaluronic acid (HA) with sodium chloride solution was used to explore the effect on its physico-chemical properties such as solution pH, viscosity, color and infrared spectroscopy and UV spectra. The results demonstrated that the irradiation treatment could decrease molecular weight, viscosity and pH of hyaluronic acid, and result in enhanced yellow color. In addition, no obvious change in absorption characteristic peaks of UV and FT-IR for the irradiated hyaluronic acid solution was observed; however, its absorption intensity was changed due to the irradiation treatment. Moreover, the irradiated hyaluronic acid exhibited a gradual increase trend of scavenging capability on DPPH free radicals in a dose-dependent manner.

Key words: hyaluronic acid, irradiation, depolymerization, physico-chemical property

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