Abstract: To observe the blood-glucose lowering effects of flavonoids extracted from sweet potato vines (FSPV) on experimental diabetic mice, the mice were divided into different groups. Each group was given FSPV or glybenclamide or normal Saline, respectively. The concentration of serum glucose were determined respectively in normal control groups and diabetic mice groups induced by alloxan. Three doses of FSPV could remarkably decrease the serum glucose of diatetic mice. On the other hand, it was found that FSPV had no significant influence on the serum glucose level of normal mice. Conclusion: FSPV had significant effects of lowering blood-glucose action on diabetic mice and was probably worthy to be developed into medicines for diabetes.

Key words: sweet potato vines, flavonoids, diabetes, declining blood-glucose effects