Abstract: As a new micro-analysis technology,Bio-chip has been visualized as the form of 21st century.The fundamental theory-molecular biotechnology and micro fabrication technology was described in unison. Present research situations of gene-chip、protein-chip and lab-on-chip were reviewed.Prospective appliation in food field was discussed on food toxicology food hygieneanalysis、food nutrition mechanism on molecule level、mezzanine selection and efficacy study genetically modified food assay.

Key words: bio-chip, food, future application