Study on L-phenylalanine Separation by Simulated Moving Bed

Abstract

Abstract: A new separation method of L-phenylalanine(L-Phe)from liquid of transformation was studied,and based on ion exchange and continuous separation by simulated moving bed(SMB)with standing wave design.The results showed that adsorption wave of L-Phe stays in zoneⅢwithout any adsorption loss,and the adsorptive capacity of L-Phe is 125g/kg resin, wheres the utilization of resin is improved.Desorption waves of asparagic acid and protein stay in zoneⅡby wake flow of the extract firm zoneⅠand desorption wave of L-Phe stays in zone L The L-Phe concentration of elution is above 35g/L,while 97.6% L-Phe is obtained from desorption by simulated moving bed with ammonia consumption(0.5mol/L)rate of L-Phe only 38.37L/kg.

Key words: L-phenylalanine, simulated moving bed, ion exchange, adsorption, desorption

WU Hao, WEI Ping, WAN Hong-Gui, HE Ruo-Ping, YU Rong-Hua, ZHANG Gan-Dao. Study on L-phenylalanine Separation by Simulated Moving Bed[J]. FOOD SCIENCE, 2007, 28(4): 64-68.

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Study on L-phenylalanine Separation by Simulated Moving Bed

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