Abstract:

D-Limonene, widely present in citrus, vegetables and spices, is a natural monoterpene. It plays an important
role in many physiological processes, such as reducing inflammation, minimizing bacterial growth, and inhibiting cancer
development. Anticancer effect is the major function of D-limonene by participating in chemical prevention, cell-cycle
inhibition, induction of apoptosis, and defense against cancer proliferation and invasiveness. D-Limonene has great prospects
for clinical application for its wide distribution, excellent safety, and convenient administration. Therefore, it is worthy of
further exploration.

Key words: D-limonene, cancer, anticancer mechanism, apoptosis