Abstract: The anti-fatigue effect of polysaccharides from Campanumoea javanica B1 (CJPs) was explored. Random mice grouping was carried out to create 4 groups including control group and polysaccharide groups at low, medium and high doses (100, 200, 400 mg/(kg ·d)). All groups were treated by gavage for 21 consecutive days. The pole-climbing time, loaded swimming time, and the contents of blood lactic acid, blood urea nitrogen and liver glycogen were measured. The results showed that CJPs could significantly prolong the pole-climbing time and loaded swimming time of mice, reduce the contents of blood lactic acid and blood urea nitrogen, and improve the content of liver glycogen when compared with the control group (P＜0.05). Therefore, CJPs have an excellent anti-fatigue effect.

Key words: Campanumoea javanica B1, polysaccharides, anti-fatigue