FOOD SCIENCE ›› 2011, Vol. 32 ›› Issue (21): 223-228.doi: 10.7506/spkx1002-6630-201121046

• Bioengineering • Previous Articles     Next Articles

Screening of Cholesterol-reducing Lactic Acid Bacteria and Its Effect on Blood Lipids in Rats

YANG Qin1,HU Ying1,GAN Sheng-li1,ZHU Qiu-jin1,2,3,*,HE La-ping1,2,3,HU Ping1,2,3,ZHU Jian-rong3,4   

  1. (1. College of Life Sciences, Guizhou University, Guiyang 550025, China;2. Food Science and Engineering Research Center, Guizhou University, Guiyang 550025, China;3. Guizhou Province Dairy Engineering Technology Research Center, Guiyang 550018, China;4. Guiyang Sanlian Dairy and Food Co. Ltd., Guiyang 550018, China)
  • Online:2011-11-15 Published:2011-11-11

Abstract: In this study, lactic acid bacteria with the ability to degrading cholesterol were screened from fermented products and human feces. Strains R-2 and I-2 had the highest cholesterol degradation rate in the MRS-CHOL culture medium among the selected strains, reaching( 26.97 ± 0.51)% and (23.72 ± 0.41)%, respectively. Both strains exhibited good tolerance to low pH (3.0). In the presence of 0.3 g/100 mL bile salt, the viable cell counts of I-2 and R-2 after 6 hours of cultivation were 1.1 × 104 CFU/mL and 2.2 × 106 CFU/mL, respectively. Moreover, R-2 and I-2 could inhibit the increase of TC (P < 0.01) and LDL-C (P <0.05) to some extent. R-2 and I-2 were identified as Enterococcus faecium and Enterococcus hirae, respectively by bacterial identification technology.

Key words: lactic acid bacteria, cholesterol-reducing, screening, fermentation, Eenterococcus, animal model

CLC Number: