Effect of Propolis on Liver Cancer Cell Proliferation and Fat Deposition

doi:10.7506/spkx1002-6630-201209052

Abstract

Abstract: The objective of this study is to preliminarily quantify the control efficacy of human liver cancer by propolis through evaluating the inhibitory effect on HCC cell proliferation and fat deposition. The content of flavonoids in propolis was determined by HLPC-MS to be (191.472±1.986) mg/g. The proliferation of proplis-treated hepatoma cells was evaluated by MTT. The tg9 group (propolis:olive oil ＝1:2, V/V) revealed the strongest inhibitory effect on cell proliferation. The triglyceride (TG) contents in all treatment groups were in the range of 410.333－459.672 nmol/L. Therefore, propolis can not control fat deposition in cells and the preventative effect of propolis on fatty liver is not satisfactory. However, it has strong inhibitory effect on the proliferation of liver cancer cells.

Key words: propolis, hepatoma cells, proliferation, fat deposition

CLC Number:

S896.6

TIANWen-li，ZHAOYa-zhou，PENGWen-jun. Effect of Propolis on Liver Cancer Cell Proliferation and Fat Deposition[J]. FOOD SCIENCE, 2012, 33(9): 247-250.

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Effect of Propolis on Liver Cancer Cell Proliferation and Fat Deposition

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