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Research Progress on Composition Structure Characteristics, Activity Mechanism and Quality Control of Kudingcha (Ligustrum robustum (Roxb.) Blume)

LING Zhizhou2, 3, 3, 3, 3, 3, 3,   

  • Received:2022-04-20 Revised:2023-03-05 Online:2023-04-15 Published:2023-04-19

Abstract: Kudingcha (Ligustrum robustum (Roxb.) Blume) is a kind of traditional medicine-food homologous plant with wide application and great economic value. It has been used as national medicine and substitute tea beverage for a long history in Guizhou, Yunnan and Sichuan provinces of China, and has attracted much attention in recent years. The chemical composition of Kudingcha (Ligustrum robustum (Roxb.) Blume) is complex, from which phenylpropanoids, phenylethanoids, monoterpenes, iridoids, flavonoids and volatile oils have been isolated. It has a wide range of pharmacological effects, including lipid-lowering, antioxidant, antiviral, antibacterial, anti-inflammatory, immune regulation and anti-cancer activities. However, in recent years, there have been few research progress on the basis of Ligustrum robustum (Roxb.) Blume, and only a few mentions have been made in the research progress of the Ligustrum or the major categories of Kudingcha, which is not conducive to the standardized research, development and utilization of Kudingcha (Ligustrum robustum (Roxb.) Blume). This paper comprehensively summarizes and expounds the research on the composition base, pharmacological activity and quality control status of Kudingcha (Ligustrum robustum (Roxb.) Blume) at home and abroad in recent years, and focuses on the structural basis characteristics and pharmacological activity mechanism of its characteristic components. This paper provides a theoretical reference for the preparation, separation, structure identification and pharmacological activity mechanism research of the subsequent characteristic components of Kudingcha (Ligustrum robustum (Roxb.) Blume).

Key words: Kudingcha, Ligustrum robustum (Roxb.) Blume, Structure characteristics, Pharmacological activities, Mechanism of action, Quality control

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