FOOD SCIENCE ›› 2010, Vol. 31 ›› Issue (21): 373-377.doi: 10.7506/spkx1002-6630-201021085

• Nutrition & Hygiene • Previous Articles     Next Articles

Combined Effect of Bovine Colostrumson and Selenium-enriched Rhodopseudomonas palustris G3 on Immune Function in Mice

YANG Qi-yin1,2,3，WANG Jia-fang1，JIA Bing-sheng1，GUAN Hai-hua1，LIU Qing1   

  1. 1. College of Life Science, Nanjing Normal University, Nanjing 210046, China；
    2. Nanjing Engineering and Technology Research Center for Microbiology, Nanjing 210046, China；
    3. Jiangsu Engineering and Technology Research Center for Microbial Resources, Nanjing 210046, China
  • Received:2010-06-25 Online:2010-11-15 Published:2010-12-29
  • Contact: YANG Qi-yin E-mail:yangqiyin@163.com

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Abstract:

In order to investigate the effect of selenium-enriched bovine colostrumson on immune function of immunodepressed mice induced by cyclophosphamide, selenium-enriched Rhodopseudomonas palustris G3 (hereinafter called selenium-enriched G3) was mixed with bovine colostrumson to prepare selenium-enriched bovine colostrumson. The immunodepressed mice were treated with selenium-enriched G3, bovine colostrumson and selenium-enriched bovine colostrumson, respectively. The administration was carried out once a day for 47 successive days after 3 days of adaptive feeding, and organ index, white blood cell number, T-cell population, the contents of SOD and GSH-Px in blood, and feed/gain ratio of mice were determined at the end of the administration. Results indicated that selenium-enriched G3, bovine colostrumson and selenium-enriched bovine colostrumson could increase the utilization efficiency of diet, enhance the activities of SOD and GSH-Px in blood, and improve mouse immune function. Compared with the control group, the selenium-enriched bovine colostrumson exhibited best improved immune at the high dosage.

Key words: selenium, bovine colostrumson, Rhodopseudomonas palustris, cyclophosphamide, immunization

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