食品科学 ›› 2011, Vol. 32 ›› Issue (11): 329-333.doi: 10.7506/spkx1002-6630-201111069

• 专题论述 • 上一篇    下一篇

多糖抗肿瘤构效关系及其机制研究进展

谢好贵,陈美珍*,张玉强   

  1. 汕头大学理学院
  • 出版日期:2011-06-15 发布日期:2011-05-13
  • 基金资助:
    广东省科技计划项目(2009B020312012;2010B020201015)

Research Progress on Structure-antitumor Activity Relationship of Polysaccharide and Its Mechanism

XIE Hao-gui,CHEN Mei-zhen*,ZHANG Yu-qiang   

  1. College of Science, Shantou University, Shantou 515063, China
  • Online:2011-06-15 Published:2011-05-13

摘要: 多糖是一类具有免疫调节、抗肿瘤、降血糖、抗病毒、抗氧化等多种生物活性的大分子物质,广泛存在于动植物与微生物中。在多糖的众多生物活性中,其抗肿瘤作用已较明确。本文主要阐述多糖抗肿瘤活性的构效关系,并对近年来国内外多糖抗肿瘤作用机制的研究进展进行概述。

关键词: 抗肿瘤, 多糖, 构效关系, 作用机制

Abstract: Polysaccharides are a class of macromolecules widely found in plants, animals and microorganisms, with various bioactive activities, including immunomodulatory, antitumor, hypoglycemic, antiviral, and antioxidant etc. Among a number of biological activities, the antitumor effect is relatively clear. This article focuses on the research progress on the structure-antitumor activity relationship and its mechanism of polysaccharides at home and abroad in recent years.

Key words: polysaccharide, antitumor, structure-activity relationship, mechanism

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