关键词: 蛋清蛋白质, 血管紧张素转化酶抑制肽, 降压机制, 构效关系, 抑制活性

Abstract:

Angiotensin converting enzyme (ACE) catalyzes the conversion of angiotensin I to potent vasoconstrictor angiotensin II and plays an important physiological role in the regulation of blood pressure. Angiotensin converting enzyme inhibitory peptides derived from animal or plant proteins have attracted extensive attention and have become a hot research topic due to their safety and no side effects. In this paper, current research progress including antihypertensive mechanisms and evaluation methods of ACE inhibitory peptides is reviewed.

Key words: egg white protein, angiotensin converting enzyme inhibitory peptide, antihypertensive mechanism, structure-activity relationship, inhibitory activity