食品科学 ›› 2010, Vol. 31 ›› Issue (11): 312-315.doi: 10.7506/spkx1002-6630-201011068

• 专题论述 • 上一篇    下一篇

抗菌肽抗氧化作用机制及其应用前景

肖明珠1,2,金小宝1,2,朱家勇1,2,*   

  1. 1.广东药学院基础学院 2.广东省药用生物活性物质研究重点实验室
  • 收稿日期:2009-11-09 修回日期:2010-04-02 出版日期:2010-06-01 发布日期:2010-12-29
  • 通讯作者: 朱家勇 E-mail:zhujy@gdpu.edu.cn
  • 基金资助:

    广东省产业技术研究与开发资金项目(2008B080703065);广东省教育部产学研合作项目(2008B090500191)

Antioxidant Mechanism and Application Prospective of Antibacterial Peptides

XIAO Ming-zhu1,2,JIN Xiao-bao1,2,ZHU Jia-yong1,2,*   

  1. 1. School of Basic Courses, Guangdong Pharmacy University, Guangzhou 510006, China ;
    2. Guangdong Key Laboratory of Pharmaceutical Bioactive Substances, Guangzhou 510006, China
  • Received:2009-11-09 Revised:2010-04-02 Online:2010-06-01 Published:2010-12-29
  • Contact: ZHU Jia-yong E-mail:zhujy@gdpu.edu.cn

摘要:

抗菌肽作为一种具有抗微生物作用的生物活性肽而成为研究热点已经20 余年,研究发现部分抗菌肽不仅具有抗微生物的特性,更有抗氧化、抗衰老作用,目前认为其抗氧化作用机制包括:清除自由基,抑制脂质过氧化以及螯合金属离子等。本文综述近10 年抗菌肽抗氧化作用机制研究进展,及其在食品、化妆品、保健品方面的应用,并展望其应用前景。

关键词: 抗菌肽, 抗氧化, 机制, 食品添加剂, 保健品

Abstract:

Antibacterial peptides have become a research hotspot of great interest in more than two decades. Besides their anti-microbial property, their anti-oxidant and anti-aging effects have been confirmed through current extensive research. In this paper, anti-oxidation mechanisms related to scavenging of free radicals, inhibition of lipid peroxidation and chelating of metal ions are reviewed. In addition, their applications in food, cosmetics and health products are also discussed.

Key words: antibacterial peptide, antioxidant activity, mechanism, food additive, health-care product

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