食品科学 ›› 2010, Vol. 31 ›› Issue (8): 74-76.doi: 10.7506/spkx1002-6300-201008017

• 工艺技术 • 上一篇    下一篇

超临界二氧化碳萃取桔核中诺米林的工艺研究

罗喜荣1,范菊娣1,莫彬彬2,杨军2   

  1. 1.贵阳医学院药学院 2.中国科学院地球化学研究所
  • 收稿日期:2009-06-16 出版日期:2010-04-15 发布日期:2010-12-29
  • 通讯作者: 杨军 E-mail:yjsfe@sina.com
  • 基金资助:

    贵州省科技基金项目(黔基合计字[2001]3002 号);贵州省工业攻关项目(黔科合GY 字[2007]3059)

Response Surface Optimization of Supercritical Carbon Dioxide Extraction of Nomilin from Citrus Seeds

LUO Xi-rong1,FAN Ju-di1,MO Bin-bin2,YANG Jun2,*   

  1. 1. School of Pharmacy, Guiyang Medical University, Guiyang 550004, China ;
    2. Institute of Geochemistry, Chinese Academy of Sciences, Guiyang 550002, China
  • Received:2009-06-16 Online:2010-04-15 Published:2010-12-29
  • Contact: YANG Jun2 E-mail:yjsfe@sina.com

摘要:

采用响应曲面法优化超临界CO2 萃取橘核中诺米林的工艺条件,考察萃取压力、萃取温度、夹带剂用量对诺米林萃取量的影响。结果表明诺米林的优化萃取条件为萃取压力25MPa、萃取温度51℃、夹带剂用量1.5mL/g,在此条件下诺米林萃取量为(6.27 ± 0.06)mg/g。

关键词: 橘核, 诺米林, 超临界CO2 萃取, 响应曲面法

Abstract:

Response surface methodology based on a central composite design involving 15 experiments of 3 variables at 3 levels was used to optimize nomilin yield at different levels of key supercritical carbon dioxide extraction parameters such as extraction pressure and temperature and entrainer (95% ethanol) dosage. Results showed that the optimal levels of these parameters for achieving a maximum nomilin yield of (6.27 ± 0.06) mg/g were as follows: extraction pressure 25 MPa, 51 ℃ and entainer dosage 1.5 mL/g.

Key words: citrus seeds, nomilin, supercritical CO2 extraction, response surface methodology

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