Protective Effect of Phenolic Compounds from Lycopus lucidus Turcz. on DNA Damage

doi:10.7506/spkx1002-6630-201823009

Abstract

Abstract: Free phenolics (FP) and insoluble cell wall-bound phenolics (ICP) from Lycopus lucidus Turcz. were obtained by ultrasound-assisted extraction. The phenolic contents were determined by the Folin-Ciocalteu method and the phenolic compositions were analyzed by high-performance liquid chromatography (HPLC). The protective effects of phenolic extracts on peroxyl radical (ROO·)-mediated DNA damage were investigated and correlated to phenolic contents. The results indicated that both the phenolic compounds possessed protective effects against ROO·-mediated DNA damage with FP being more effective. Significant positive correlations were observed between ICP from L. lucidus Turcz. on December 15th, 2016 and January 14th, 2017 and protective effects on DNA damage (P < 0.05).

Key words: Lycopus lucidus Turcz., phenolic compounds, peroxyl radicals, DNA damage, protective effect

CLC Number:

TS201.2

GUO Qi, GAO Chunyan. Protective Effect of Phenolic Compounds from Lycopus lucidus Turcz. on DNA Damage[J]. FOOD SCIENCE, 2018, 39(23): 54-59.

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Protective Effect of Phenolic Compounds from Lycopus lucidus Turcz. on DNA Damage

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