食品科学 ›› 2012, Vol. 33 ›› Issue (11): 323-327.doi: 10.7506/spkx1002-6630-201211067

• 专题论述 • 上一篇    下一篇

微生物转化法制备人参皂苷Compound K 的研究进展

李 学,臧 埔,张连学*,郜玉钢*,李 萍,郝建勋,王亚星   

  1. 吉林农业大学中药材学院
  • 出版日期:2012-06-15 发布日期:2012-07-27
  • 基金资助:
    科技部科技人员服务企业行动计划项目(2009GJB10031);第46 批中国博士后科学基金项目(20090461042); 科技部科技支撑计划项目(2011BAI03B01);国家自然科学基金项目(31070316);科技部科技成果转化项目 (2010GB2B100100);吉林省科技条件与平台建设计划项目(20112101)

Research Progress on Ginsenoside CK Production by Microbial Transformation

LI Xue,ZANG Pu,ZHANG Lian-xue*,GAO Yu-gang*,LI Ping,HAO Jian-xun,WANG Ya-xing   

  1. (College of Traditional Chinese Medicine, Jilin Agricultural University, Changchun 130118, China)
  • Online:2012-06-15 Published:2012-07-27

摘要: 稀有人参皂苷Compound K(CK)是二醇型非天然人参皂苷,是其他二醇型人参皂苷在人体肠道内的降解产物。因其在抗肿瘤等方面有特效,需大量制备以满足医疗和科研需要,因此,有效获得稀有人参皂苷CK已开展了大量研究。本文就人参皂苷CK的微生物转化及制备进行系统的综述,旨在为其进一步开发利用提供参考。

关键词: 人参, 人参皂苷CK, 微生物转化

Abstract: Rare ginsenoside compound K (CK) is a non-natural diol-type saponin. It is a metabolic product from other diol-type saponins in human intestine. Due to its anti-tumor and other beneficial effects, plenty of ginsenoside CK are needed to meet the needs of medical care and scientific research. For this resson, attempts have been done to produce ginsenoside CK effectively under human controlled conditions. In this paper, we review recent progress on ginsenoside CK preparation by microbial transformation, with the purpose to provide some references for future development of better methods to produce ginsenoside CK.

Key words: ginseng, ginsenoside CK, microbiao transformation

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