食品科学 ›› 2020, Vol. 41 ›› Issue (23): 329-337.doi: 10.7506/spkx1002-6630-20191205-059

• 专题论述 • 上一篇    下一篇

食源性Fe2+/Fe3+结合活性肽的研究进展

林善婷,胡晓,李来好,杨贤庆   

  1. (1.中国水产科学研究院南海水产研究所,农业农村部水产品加工重点实验室,广东 广州 510300;2.南京农业大学无锡渔业学院,江苏 无锡 214081)
  • 出版日期:2020-12-15 发布日期:2020-12-28
  • 基金资助:
    现代农业产业技术体系建设专项(CARS-46);广东省自然科学基金项目(2017A030313164); 广东省基础与应用基础研究基金项目(2019A1515011588);广东省科技创新战略专项资金计划项目(2018S0044); “扬帆计划”引进创新创业团队专项(2015YT02H109);中国水产科学研究院基本科研业务费资助项目(2020TD69)

Recent Progress in Fe2+/Fe3+ Chelating Peptides Derived from Foods

LIN Shanting, HU Xiao, LI Laihao, YANG Xianqing   

  1. (1. Key Laboratory of Aquatic Product Processing, Ministry of Agriculture and Rural Affairs, South China Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Guangzhou 510300, China; 2. Wuxi Fisheries College, Nanjing Agricultural University, Wuxi 214081, China)
  • Online:2020-12-15 Published:2020-12-28

摘要: 铁离子是构成人体组织和维持正常生理功能所必需的微量营养元素,当体内缺乏铁离子时易导致许多营养缺乏症。Fe2+/Fe3+结合活性肽是一种具有结合Fe2+/Fe3+能力,并可与之形成可溶性结合物的肽类物质,其在生物体内可促进铁离子的吸收。本文从Fe2+/Fe3+结合活性肽的食物来源、制备、分离纯化、结构特征以及肽-Fe2+/3+结合物的形成、结合位点、促Fe2+/Fe3+吸收机制等方面进行综述,以期为Fe2+/Fe3+结合活性肽的研究及产品开发提供参考。

关键词: Fe2+/Fe3+结合活性肽;肽-Fe2+/3+结合物;结构特征;生物活性;吸收机制

Abstract: Iron ion is a necessary micronutrient for constituting human tissues and maintaining normal physiological functions. Iron deficiency in the body is prone to cause many nutritional deficiencies. Fe2+/Fe3+ chelating peptide is a kind of peptide that has the ability to chelate Fe2+/Fe3+ forming a soluble conjugate, which can promote the absorption of iron in the body. This paper summarizes the food sources, preparation, separation and purification, and structural characteristics of Fe2+/Fe3+ chelating peptides, as well as the formation and chelating sites of peptide-Fe2+/3+ complexes and the mechanism for promoting Fe2+/Fe3+ absorption, in order to provide a theoretical basis for the research and product development of Fe2+/Fe3+ chelating peptide.

Key words: Fe2+/Fe3+ chelating peptide; peptide-Fe2+/3+ complexes; structural characteristics; biological activities; absorption mechanism

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