食品科学 ›› 2025, Vol. 46 ›› Issue (2): 118-125.doi: 10.7506/spkx1002-6630-20240621-148

• 营养卫生 • 上一篇    下一篇

全谷物及杂豆添加量在小鼠与人体间剂量换算分析

支莉,朱益清,赵亮星,陈睿,赵卿宇,王超,薛勇,沈群   

  1. (国家粮食产业(青稞深加工)技术创新中心,国家粮油标准测试研究中心,中国农业大学食品科学与营养工程学院,北京 100083)
  • 出版日期:2025-01-25 发布日期:2024-12-30
  • 基金资助:
    “十四五”国家重点研发计划重点专项(2022YFF1100505)

Dietary Dose Conversion of Whole Grains and Non-soy Legumes between Mice and Humans

ZHI Li, ZHU Yiqing, ZHAO Liangxing, CHEN Rui, ZHAO Qingyu, WANG Chao, XUE Yong, SHEN Qun   

  1. (National Center of Technology Innovation (Deep Processing of Highland Barley) in Food Industry, National Research Center for Grain and Oil Standards Testing, College of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083, China)
  • Online:2025-01-25 Published:2024-12-30

摘要: 适量摄入全谷物及杂豆可以改善糖代谢和脂代谢,但摄入量过高可能产生不利影响。由于缺乏相应的换算关系,小鼠饲料中的摄入量无法直接作为人群摄入量的参考。本文介绍小鼠饲料中常见的全谷物及杂豆的添加量,并通过等效系数法、比表面积法、体型系数法、食物比重法、体表面积指数法、能量换算法和营养素换算法探讨了小鼠饲料中全谷物及杂豆添加量与人群膳食推荐量之间的剂量效应关系。研究表明,当人群全谷物及杂豆推荐摄入量为50~150 g时,相当于在每日进食量为3 g的小鼠饲料中添加5%~50%的全谷物及杂豆。对于小鼠而言,饲料中全谷物及杂豆的添加量超过50%可能存在过量摄入的风险。本研究为未来建立全谷物及杂豆在小鼠饲料添加量与人群推荐摄入量之间的换算关系提供了重要参考。

关键词: 剂量换算;全谷物;杂豆;体表面积

Abstract: Moderate intake of whole grains and non-soy legumes can improve glucose and lipid metabolism, but excessive intake may have an adverse effect. Due to the lack of corresponding conversion relationships, the intake of whole grains and non-soy legumes in mouse feed cannot directly serve as a reference for human intake. This paper introduces the addition levels of common whole grains and non-soy legumes in mouse feed and explores their relationship with the recommended dietary intakes (RDI) of common whole grains and non-soy legumes in humans using various methods, including equivalent coefficient, surface area ratio, body shape coefficient, food density, body surface area index, energy conversion, and nutrient conversion methods. The results indicate that the RDI of 50–150 g of whole grains and non-soy legumes in humans could be equivalently converted into addition of 5%–50% whole grains and beans in the feed of mice with a 3 g daily feed intake. Dietary addition of whole grains and non-soy legumes exceeding 50% might place mice at risk for overconsumption. This study provides an important reference for establishing the conversion relationship between the amounts of whole grains and non-soy legumes added to mouse feed and the RDI of whole grains and non-soy legumes in humans.

Key words: dose conversion; whole grains; non-soy legumes; body surface area

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