食品科学 ›› 2025, Vol. 46 ›› Issue (17): 153-147.doi: 10.7506/spkx1002-6630-20250325-201

• 营养卫生 • 上一篇    

溶剂法分提对阿勒泰羊臀脂的脂肪酸分布及其对小鼠血脂水平影响机制

马欣,徐泽权,朱明睿,吴玲艳,王子荣   

  1. (新疆农业大学食品科学与药学学院,新疆?乌鲁木齐 830052)
  • 发布日期:2025-08-18
  • 基金资助:
    国家自然科学基金地区科学基金项目(32260558);新疆维吾尔自治区自然科学基金项目(2022D01B102)

Mechanistic Studies on the Effects of Solvent Fractionation on the Fatty Acid Distribution of Altay Sheep Tail Fat and Blood Lipids in Mice

MA Xin, XU Zequan, ZHU Mingrui, WU Lingyan, WANG Zirong   

  1. (College of Food Science and Pharmacy, Xinjiang Agricultural University, ürümqi 830052, China)
  • Published:2025-08-18

摘要: 以阿勒泰羊臀脂及其分提产物为研究对象,比较分析羊脂臀及其分提产物的理化特性和脂肪酸组成,并模拟中国城镇部分居民油脂摄入情况进行动物实验,研究其对小鼠血脂代谢的影响。结果表明:阿勒泰羊臀脂经分提后低熔点分提产物(2 ℃液油)中不饱和脂肪酸相对含量最高,达到52.03%,高熔点分提产物(32 ℃固脂)饱和脂肪酸相对含量最高,为54.21%。动物实验表明,2 ℃液油组小鼠肥胖程度最低,菜籽油组肥胖程度最高,各分提产物组与空白对照组无显著差异;各实验组之间脏器指数差异不显著。通过血脂水平发现2 ℃液油组高密度脂蛋白胆固醇浓度最高,为2.78 mmol/L;32 ℃固脂组甘油三酯浓度最高;菜籽油组低密度脂蛋白胆固醇浓度最低,但与2 ℃液油组相比差异不显著(P>0.05);各组总胆固醇浓度无显著差异(P>0.05)。总体来看,2 ℃液油在各分提组中不论从营养角度还是食用健康性都具有明显优势,本研究或可为动物油脂食用多样性、服务“健康中国”提供一定参考价值。

关键词: 阿勒泰羊臀脂;分提产物;脂肪酸;血脂水平

Abstract: This study investigated the physicochemical properties and fatty acid composition of Altay sheep tail fat and its fractionated products and conducted animal experiments simulating the dietary fat intake pattern of urban residents in China to evaluate their effects on blood lipid metabolism in mice. The results showed that the low-melting-point fraction (liquid at 2 ℃) exhibited the highest unsaturated fatty acid content (52.03%), while the high-melting-point fraction (solid at 32 ℃) had the highest saturated fatty acid content (54.21%). The animal experiments indicated that mice gavaged with the liquid fat showed the lowest obesity level, whereas the rapeseed oil group had the highest body mass index (BMI). Each fraction showed no significant difference in degree of obesity compared with the control group. There were no significant differences between any of the experimental groups in organ coefficients. The blood lipid profile analysis showed that the 2 ℃ liquid fat group had the highest high-density lipoprotein cholesterol (HDL-C) level (2.78 mmol/L). The 32 ℃ solid fat group showed the highest triglyceride (TG) concentration. The lowest level of low-density lipoprotein cholesterol (LDL-C) was found in the rapeseed oil group, which showed no significant difference compared with the liquid fat group (P > 0.05). Furthermore, there was no intergroup difference in total cholesterol (TC) concentrations (P > 0.05). Overall, the liquid fat fraction had significant advantages in both nutritional and health aspects. This study provides valuable insights for the development of Altay sheep tail fat as a functional edible lipid source.

Key words: Altay sheep tail fat; fractionated products; fatty acids; blood lipid levels

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