食品科学 ›› 2025, Vol. 46 ›› Issue (23): 401-415.doi: 10.7506/spkx1002-6630-20250804-037

• 专题论述 • 上一篇    

地黄功能性糖的结构特征及生物活性研究进展

李云丹,衡疆英,张瑜,张岩,马璇,何逸,刘博,靳静,闫文杰,王锋   

  1. (1.北京联合大学生物化学工程学院,北京 100023;2.河北省食品检验研究院 河北省食品安全实验室,河北 石家庄 050227)
  • 发布日期:2025-12-26
  • 基金资助:
    河南省重大科技专项(231100310200);“十四五”国家重点研发计划重点专项(2023YFF1103804); 北京联合大学校级科研项目(ZK20202516)

Research Progress on Structural Characteristics and Biological Activities of Functional Sugars from Rehmannia glutinosa

LI Yundan, HENG Jiangying, ZHANG Yu, ZHANG Yan, MA Xuan, HE Yi, LIU Bo, JIN Jing, YAN Wenjie, WANG Feng   

  1. (1. College of Biochemical Engineering, Beijing Union University, Beijing 100023, China; 2. Hebei Food Safety Laboratory, Hebei Food Inspection and Research Institute, Shijiazhuang 050227, China)
  • Published:2025-12-26

摘要: 地黄常以生地黄、熟地黄形式被广泛研究。鲜地黄由于不耐储存,所以当前研究不多。2024年8月国家卫生健康委员会允许地黄用于食品,使鲜地黄具有一定研究价值。糖类物质为地黄提供风味和功能活性,因此明确鲜地黄功能性糖的结构和含量对鲜地黄食品开发具有重要意义。当前存在鲜地黄基础数据缺乏、构效关系不明确、加工对结构-活性影响机制不清等问题,本文通过总结不同加工形式的地黄中功能性糖的结构和活性差异,初步推测鲜地黄具有较好的抗氧化、抗炎、抗肿瘤活性,其抗氧化活性优于生地黄和熟地黄。在口感方面,鲜地黄肉质脆嫩,汁液丰富,滋味微甜带苦,为鲜地黄功能性食品的开发提供了口感优势。本文为开发鲜地黄食品提供了一定理论依据。

关键词: 地黄;多糖;寡糖;功能活性;药食同源

Abstract: While both raw and prepared Rehmannia glutinosa are widely studied, there is currently limited research on fresh R. glutinosa due to its poor storability. In August 2024, China’s National Health Commission approved the use of R. glutinosa as a food ingredient, making fresh R. glutinosa worthy of research. Carbohydrates contribute to the flavor and functional activity of R. glutinosa. Therefore, clarifying the structure and content of functional carbohydrates in fresh R. glutinosa is of great significance for the development of fresh R. glutinosa-based foods. Currently, several key issues exist in the research on fresh R. glutinosa including lack of basic data, unclear understanding of structure-activity relationships, and insufficient insights into how processing affects them. This paper systematically compares the differences in the structure and activity of functional sugars in fresh, raw, and prepared R. glutinosa, preliminarily inferring that fresh R. glutinosa has good antioxidant, anti-inflammatory and antitumor activities, and its antioxidant activity is superior to that of raw and prepared R. glutinosa. Fresh R. glutinosa has a tender, crisp texture and is very juicy. It offers a mild sweetness with a slight bitterness. Thus, fresh R. glutinosa has advantages in texture and taste for the development of functional foods. This review provides a theoretical basis for the development of fresh R. glutinosa-based food products.

Key words: Rehmannia glutinosa; polysaccharides; oligosaccharides; functional activity; medicine and food homology

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