关键词: 白首乌C21甾甙, 剧烈运动小鼠模型, 内源性自由基, 抗氧化作用

Abstract:  The function of Baishouwu C21 steroidal glycosides(general glycosides) in resisting oxidation damage caused by endogenous free radicals was studied with exeperimental model of violent exercise mice.Five experiments were carride out,including anti-osmosis of erythrocytes, the content of peroxidated lipids and the activity of superoxide dismutase(SOD)of the liver,the activity of catalase(CAT)of erythrocytes,and the activity of GSH-peroxidase(GSH-Px)of the blood.The results indicated that exhaustive exercise cause not only the increase of the osmosis of erythrocytes and the content of peroxidated lipids of the liver,but also the decrease of the activity of all the three inner anti-oxidation enzymes namely SOD,CAT and GSH-Px;and that general glycosides could restrain from such oxidative damage induced by exhaustive exercise.This suggested that by both of their direct scavenging capacity on oxygen free radicals and the activation of the anti-oxidation.immune system,general glycosides could enhance the anti-oxidation capability of the organ and reduce the damage of free radicals to the organ to chieve anti-ageing and health benefit effect.

Key words:  , Baishouwu C21 Steroidal glycosides Experimental model of violent excise mice Endogenous free radical Anti-oxidation function；