食品科学 ›› 2005, Vol. 26 ›› Issue (9): 408-410.

• 分析检测 • 上一篇    下一篇

免疫增强型肠内营养制剂HI-NUTRI对小鼠营养指标和免疫功能的影响

 李丽丽, 任发政, 张联, 潘卫松, 张耀春   

  1. 中国农业大学食品科学与营养工程学院,教育部功能乳品重点实验室,北京大学临床肿瘤学院,中国医学科学院药用植物研究所
  • 出版日期:2005-09-15 发布日期:2011-09-20

Effect of Immune-enhanced Enteral Nutritional Preparations on Trophic and Immune Index of Mice

 LI  Li-Li, REN  Fa-Zheng, ZHANG  Lian, PAN  Wei-Song, ZHANG  Yao-Chun   

  1. 1.College of Food Science and Nutritional Engineering of China Agriculture University, The Key Laboratory of Functional Dairy of Ministry of Education;2.School of Oncology of Peking University;3.Institute of Medicine Plant Development of Chinese Academy of Medical Sciences
  • Online:2005-09-15 Published:2011-09-20

摘要: 本实验以正常小鼠淋巴细胞增殖能力、巨噬细胞的吞噬功能和NK细胞的杀伤活性作为指标,对免疫增强型肠内营养制剂的免疫促进功能进行了研究。结果表明:该产品能维持小鼠正常的生理生化功能,对小鼠的免疫功能有一定的促进作用,其中低浓度免疫增强配方能显著提高小鼠的NK细胞杀伤活性(p<0.05),明显刺激小鼠脾淋巴细胞增殖,免疫增强效果与进口产品相当。

关键词: 肠内营养制剂, 免疫, 免疫调节, 淋巴细胞增殖, NK细胞

Abstract: Multiplication of lymphocyte, phagocytosis of Macrophage and killing ability of NK cell of Mice spleen were used as index to study the immunoregulation activity of immune-enhanced enteral nutritional preparations in this paper. The results shown that the immune-enhanced preparations could remain the normal physiochemical function of mice, stimulate the immune functions of normal rats in certain extent, especially the low concentration immune enhanced formula. It can improve the proliferation of lymphocyte and the killing ability of NK cell of mice spleen evidently, and has an equal impact to the import immune enhanced preparation.

Key words: enteral nutritional preparation, immune, immunoregulation, lymphocyte multiplication, natural killercell