食品科学 ›› 2006, Vol. 27 ›› Issue (10): 641-644.

• 专题论述 • 上一篇    下一篇

母乳中免疫成分及其对婴儿免疫发育作用的研究进展

 杨静静,  庞广昌   

  1. 天津商学院天津市食品生物技术重点实验室
  • 出版日期:2006-10-15 发布日期:2011-11-16

The Immunological Components in Human Milk and Their Effect on the Immune Development of Infants

 YANG  Jing-Jing,   Pang-Guang-Chang   

  1. Tian jin Key Laboratory of Food Biotechnology, Tianjin University of Commerce, Tianjin 300134, China
  • Online:2006-10-15 Published:2011-11-16

摘要: 人们对乳的研究有着悠久的历史,随着人们对母乳中多种生物活性物质认识的逐渐加深,科学家们发现这些活性物质不仅可以保护婴儿免受病原菌感染,而且还可以促进婴儿发育并调节婴儿的免疫系统。母乳是母亲的免疫系统向婴儿的转移。母乳中许多免疫成分的生理和保护性功能可以通过对婴儿及动物模型和体外实验的研究得以证实。本文综述了母乳中的免疫成分及其对婴儿免疫发育的作用,并主要论述了母乳中“传统的”免疫和非免疫成分对免疫发育的促进作用及对婴儿免疫应答的调控。

关键词: 母乳, 婴儿, 免疫, 细胞因子

Abstract: There has been a long history for the research on the human milk and the components in the breast milk. With the considerable advances of our understanding in the bioactive components in human milk, it has been recognized that milk not only provides protection against pathogens, but also facilitates immune development and an appropriate immune response in infants. Human milk is the transfer of maternal immune system from mothers to infants. The physiological and protective functions can be deduced from a great deal of studies not only in infants but in other species and in vitro models. The paper reviews the immune components in human milk and immune development in infants and focuses on the current advances on how the‘ traditional’ immune and nonimmune components identified in human milk promote immune development of infants and regulate the immune responses in infants.

Key words: human milk, infants, immune, cytokines