食品科学 ›› 2007, Vol. 28 ›› Issue (9): 621-626.

• 专题论述 • 上一篇    下一篇

乳酸及其代谢工程生产

 李可伟, 庞广昌   

  1. 天津商业大学天津市食品生物技术重点实验室; 天津商业大学天津市食品生物技术重点实验室 天津300134; 天津300134;
  • 出版日期:2007-09-15 发布日期:2011-11-22

Lactic Acid and Metabolic Engineering for Lactic Acid Production

 LI  Ke-Wei, PANG  Guang-Chang   

  1. Tianjin Key Labotary of Food Biotechnology,Tianjin University of Commerce,Tianjin 300134,China
  • Online:2007-09-15 Published:2011-11-22

摘要: 乳酸是一种具有重要工业价值的有机酸。在体内,乳酸不仅是一种能源物质,而且可能作为一种信号分子,对维持机体代谢网络的平衡起到了重要作用。本文分析了目前乳酸生产存在的主要问题,介绍了近年来应用代谢工程改进乳酸生产的一些实践,并展望了代谢工程用于乳酸生产的潜能及发展趋势。

关键词: 乳酸, 乳酸脱氢酶, 代谢工程, 产率

Abstract: Lactic acid is an important organic acid of industrial importance.It is not only an energy resource for organism,but also important for the balance of metabolic networks as a potential signal molecule.Here,the chief problems encountered during lactic acid production today were analysed,some practices recently that using metabolic engineering approaches to improve lactic acid production were introduced,and the potential and trend for lactic acid production using metabolic engineering approaches were expected.

Key words: lactic acid, lactate dehydrogenase(LDH), metabolic engineering, yield