食品科学 ›› 2008, Vol. 29 ›› Issue (1): 314-316.

• 营养卫生 • 上一篇    下一篇

泡菜对大鼠血脂的调节作用研究

 蒋和体, 卢新军   

  1. 西南大学食品科学学院; 西南大学食品科学学院 重庆400716; 重庆400716;
  • 出版日期:2008-01-15 发布日期:2011-07-28

Recuperative Effects of Pickles on Hyperlipidemia Rats

 JIANG  He-Ti, LU  Xin-Jun   

  1. College of Food Science, Southwest University, Chongqing 400716, China
  • Online:2008-01-15 Published:2011-07-28

摘要: 观察泡菜对高血脂大鼠血脂的影响。将SD大鼠32只随机分为4组:正常对照组、高脂模型组、低剂量组和高剂量组,每组8只。造模成功后,高脂模型组每天给予脂肪乳剂灌胃(15ml/kg bw)和生理盐水(10ml/kg bw)灌胃各一次;低剂量组每天给予脂肪乳剂灌胃(10ml/kg bw)和泡菜匀浆(10ml/kg bw)灌胃各一次;高剂量组每天给予脂肪乳剂灌胃(10ml/kg bw)和泡菜匀浆(15ml/kg bw)灌胃各一次;正常对照组以与高脂组等量的生理盐水灌胃。分别于以泡菜灌胃10d和20d后空腹取血,检测血清TC、TG和HDL-C水平。数据分析表明:与高脂对照组相比,两个泡菜剂量组大鼠血清TC、TG水平均显著下降(p<0.05),HDL-C水平只有高剂量组大鼠灌胃20d后显著增高(p<0.05)。泡菜对大鼠血脂具有一定的调节作用。

关键词: 泡菜, 血脂, 调节

Abstract: To study the recuperative effects of pickles on serum lipid level in hyperlipidemia rats. 32 male SD rats were divided into 4 groups: normal diet group as control, high fat group, low pickle dosage group and high twice pickle dasage group. Rats of normal diet group as control were fed with normal diet+normal saline(10 ml/kg bw) one time one day respectively, rats of high fat model group were given a gastric perfusion of intralipid (15 ml/kg bw)and a astric perfusion of normal saline(10 ml/ kg bw); rats of high pickle dosage group were given a astric perfusion of pickle (10ml/kg bw) and a gastric perfusion of intralipid (15 ml/kg bw); rats of low dosage pickle group were given a astric perfusion of pickle (10ml/kg bw) and a gastric perfusion of intralipid (10 ml/kg bw). After 10 days and 20 days, the serum lipid level of TC, TG and HDL-C detected. Results showed that Compared with the high fat model group, the TC, TG level of rats of two pickle groups were declined significantly (p<0.05); and only the HDL-C level of rats of high pickle dosage group increased significantly (p<0.05). Gastric perfusion of pickle may reduce serum lipid level.

Key words: pickle, serum lipid, reduction