鹿茸多肽对小鼠耐缺氧和抗疲劳能力的影响

食品科学 ›› 2008, Vol. 29 ›› Issue (4): 386-388.

鹿茸多肽对小鼠耐缺氧和抗疲劳能力的影响

罗翔丹, 潘风光, 张铁华, 张鸣镝, 宋歌, 刘静波

吉林大学军需科技学院；吉林大学军需科技学院；

出版日期:2008-04-15 发布日期:2011-08-24

Effects of Pilose Antler Polypeptide on Ability of Mice Anti-anoxia and Anti-fatigue

LUO Xiang-Dan, PAN Feng-Guang, ZHANG Tie-Hua, ZHANG Ming-Di, SONG Ge, LIU Jing-Bo

College of Quartermaster Technology, Jilin University

Online:2008-04-15 Published:2011-08-24

摘要/Abstract

摘要： 实验观察鹿茸多肽(piloseantlerpolypeptide,PAP)对小鼠耐缺氧和抗疲劳能力的影响。实验设立对照组和实验组(PAP低剂量、中剂量和高剂量组),其中实验组灌胃给予高、中、低剂量的PAP,对照组灌胃给予同低剂量PAP组相同体积的生理盐水。连续灌胃30d,常压耐缺氧法观察小鼠存活时间,断头缺氧缺血法观察小鼠张口喘气时间,并观察小鼠爬杆时间、负重游泳时间,测定游泳前、游泳后0min和20min血清乳酸含量的变化。结果显示PAP能显著增加小鼠常压缺氧存活时间、断头喘气时间、爬杆时间和负重游泳时间;并能显著降低游泳后血清乳酸的增加量。说明PAP能够提高小鼠耐缺氧和抗疲劳的能力。

关键词: 鹿茸多肽, 小鼠, 耐缺氧, 抗疲劳

Abstract: Experimental observation of the effects of pilose antler polypeptide on the ability of mouse anti-anoxia and anti- fatigue. All of the mice were divided into two groups, each consisting established control group and experimental group (PAP low- dose, medium-dose and high-dose group), which was given PAP, according to the dose of the experimental group, the control group was given a low dose with the volume of normal saline group. Gavage for 30days, the mice in each group was observed atmospheric anti-anoxia survival time; Decapitated after pant time; Climbing-time and loaded swimming time.And the same time, determination before swimming, swimming 0 minutes and 20 minutes of serum lactate content changes. The results showed that PAP can be significantly increased in mice atmospheric anti-anoxia survival time, decapitated after pant time, climbing-time and loaded swimming time; significantly decreased after swimming the increase in serum lactate. It is concluded that PAP can improve the ability of mouse anti-anoxia and anti-fatigue.

Key words: PAP, mouse, anti-anoxia, anti-fatigue

罗翔丹, 潘风光, 张铁华, 张鸣镝, 宋歌, 刘静波. 鹿茸多肽对小鼠耐缺氧和抗疲劳能力的影响[J]. 食品科学, 2008, 29(4): 386-388.

LUO Xiang-Dan, PAN Feng-Guang, ZHANG Tie-Hua, ZHANG Ming-Di, SONG Ge, LIU Jing-Bo. Effects of Pilose Antler Polypeptide on Ability of Mice Anti-anoxia and Anti-fatigue[J]. FOOD SCIENCE, 2008, 29(4): 386-388.

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