食品科学 ›› 2010, Vol. 31 ›› Issue (17): 148-152.doi: 10.7506/spkx1002-6630-201017034

• 基础研究 • 上一篇    下一篇

5种野生浆果的体外抗氧化和抗细胞增殖活性

樊梓鸾1,王振宇1 , 2 ,*,程翠林1,赵海田1,张 华1   

  1. 1.哈尔滨工业大学食品科学与工程学院
    2.东北林业大学林学院
  • 收稿日期:2010-06-30 修回日期:2010-08-19 出版日期:2010-09-15 发布日期:2010-12-29
  • 通讯作者: 王振宇 E-mail:wangzy219001@163.com

Antioxidant and Antiproliferative Activities of Five Wild Berries

FAN Zi-luan1,WANG Zhen-yu1,2,*,CHENG Cui-lin1,ZHAO Hai-tian1,ZHANG Hua1   

  1. 1. College of Food Science and Engineering, Harbin Institute of Technology, Harbin 150090, China;
    2. School of Forestry, Northeast Forestry University, Harbin 150040, China
  • Received:2010-06-30 Revised:2010-08-19 Online:2010-09-15 Published:2010-12-29
  • Contact: WANG Zhen-yu E-mail:wangzy219001@163.com

摘要:

选取东北大兴安岭地区的特色浆果花楸(Sorbus pohuashanensis H.)、蓝莓(Vaccinium uliginosum L.)、蓝靛果(Lonicera caerulea L.)、沙棘(Hippophae rhamnoides L.)、草莓(Fragaria orientalis Los.)的成熟果实,采用80% 丙酮提取,分别测定多酚、黄酮、花色苷含量,并研究其抗氧化活性和抗细胞增殖活性。结果表明:花楸的多酚和黄酮含量最高;蓝靛果的花色苷含量最高,为(367.5 ± 8.7)g/100g;5 种浆果都具有较好的体外抗氧化活性,花楸显示了最高的抑制癌细胞增殖效应。

关键词: 浆果, 多酚, 抗氧化, 抗细胞增殖

Abstract:

Some wild berries have been shown to have the functions of protecting against cardiovascular diseases, diabetes, and cancers due to the existence of phenolics. In the present study, the ripe fruits of five wild berries, Sorbus pohuashanensis H. (rowanberry), Vaccinium uliginosum L. (blue honeysuckle), Lonicera caerulea L., Hippophae rhamnoides L., and Fragaria orientalis Los., selected from the Greater Higgnan Mountains area of Northeast China were extracted with 80% acetone and the extracts were measured for their contents of total phenolics, total flavonoids and anthocyanins, ABTS+·, DPPH and total oxyradical scavenging capacities and anti-proliferative activities against HepG2 and HT29 cell (MTS assay). The results showed that rowanberry had the highest contents of total phenolics and total flavonoids among all the five berries, while blue honeysuckle had the highest anthocyanin content (367.5 ± 8.7) g/100 g. All the five berry extracts could exert antioxidant activities in vitro, of which rowanberry showed the highest inhibition effects on the proliferation of HepG2 and HT29 cells. As a conclusion, rowanberry has a huge potential for being developed as effective cancer drugs.

Key words: berries, phenolics, antioxidant activity, antiproliferative activity

中图分类号: