食品科学 ›› 2024, Vol. 45 ›› Issue (17): 335-347.doi: 10.7506/spkx1002-6630-20231208-070

• 专题论述 • 上一篇    下一篇

海洋多糖的结构、组成及其抑制肥胖作用机制的研究进展

王馥仪, 于双, 董新玉, 陈碧漪, 李莹, 赵前程, 桑雪   

  1. (1.大连海洋大学食品科学与工程学院,辽宁 大连 116023;2.大连鑫玉龙海洋生物种业科技股份有限公司,辽宁 大连 116200;3.大连市特色海洋功效成分开发与高值化利用重点实验室,辽宁 大连 116023;4.辽宁省海洋健康食品工程研究中心,辽宁 大连 116023)
  • 出版日期:2024-09-15 发布日期:2024-09-09
  • 基金资助:
    2023中央财政对辽宁渔业补助项目;辽宁省教育厅重点攻关项目(LJKZZ20220090); 国家自然科学基金青年科学基金项目(32302093);辽宁省自然科学基金计划项目(2022-BS-275); 辽宁省教育厅青年项目(LJKQZ20222401);大连海洋大学博士启动项目(HDYJ202201)

Research Progress in Structure, Composition and Antiobesity Mechanism of Marine Polysaccharides

WANG Fuyi, YU Shuang, DONG Xinyu, CHEN Biyi,, LI Ying,, ZHAO Qiancheng, SANG Xue   

  1. (1. College of Food Science and Engineering, Dalian Ocean University, Dalian 116023, China;2. Dalian Xinyulong Marine Organisms Seed Industry Technology Co. Ltd., Dalian 116200, China; 3. Dalian Key Laboratory for the Development and High Value Utilization of Characteristic Marine Functional Ingredients, Dalian 116023, China; 4. Liaoning Provincial Marine Health Food Engineering Research Centre, Dalian 116023, China)
  • Online:2024-09-15 Published:2024-09-09

摘要: 肥胖已成为全球导致死亡的第五位风险因素,寻找具有肥胖症预防及治疗作用的益生元是当前研究的热点。海洋多糖是从海洋生物中提取分离的一类特殊的生物活性物质,由于海洋的特殊环境,海洋来源多糖存在新颖的结构特征,同时,也具有独特的生物活性。基于海洋多糖通过调节糖脂代谢、炎症因子水平以及肠道菌群治疗肥胖具有极好的潜力,本文综述海洋多糖的种类、结构和组成对抑制肥胖的影响及其作用机制,重点讨论海洋多糖通过肠道菌群抑制肥胖的途径,并对海洋多糖抑制肥胖进行了展望,旨在为海洋多糖抑制肥胖药物的开发提供依据。

关键词: 海洋多糖;结构;组成;抑制肥胖;作用机制

Abstract: Globally, obesity has become the fifth leading risk factor for death, and discoverying prebiotics with preventive and therapeutic effects on obesity is a hot topic in current research. Marine polysaccharides, a special class of bioactive substances from marine organisms, have novel structural features and unique bioactivities due to the unique environment of the ocean. Marine polysaccharides have an excellent potential to treat obesity by regulating glucose and lipid metabolism, inflammatory factor levels, and the gut microbiota. This article reviews the types of marine polysaccharides, the effects of their structures and compositions on their antiobesity activity, and the underlying mechanisms of action. With the aim of providing a basis for the development of antiobesity drugs using marine polysaccharides, the article focuses on discussing the signaling pathways by which marine polysaccharides inhibit obesity through the gut microbiota, and gives an outlook on the application of marine polysaccharides for obesity inhibition.

Key words: marine polysaccharides; structure; composition; antiobesity; action mechanism

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