食品科学 ›› 2026, Vol. 47 ›› Issue (2): 357-365.doi: 10.7506/spkx1002-6630-20250828-189

• 专题论述 • 上一篇    下一篇

乳清蛋白热稳定性改性技术及评价研究进展

董暄,逄晓阳,路茹青,王筠钠,于景华,吕加平,张书文,李红娟   

  1. (1.中国农业科学院农产品加工研究所,北京 100193;2.天津科技大学食品科学与工程学院,天津 300457)
  • 出版日期:2026-01-25 发布日期:2026-02-05
  • 基金资助:
    云南省重大专项(202402AE090033);克拉玛依市重点研发计划项目(2024zdyf0007); 国家奶牛产业技术体系项目(CARS-36)

Research Progress on the Improvement and Evaluation of the Heat Stability of Whey Protein

DONG Xuan, PANG Xiaoyang, LU Ruqing, WANG Yunna, YU Jinghua, LÜ Jiaping, ZHANG Shuwen, LI Hongjuan   

  1. (1. Institute of Food Science and Technology, Chinese Academy of Agricultural Science, Beijing 100193, China;2. College of Food Science and Engineering, Tianjin University of Science and Technology, Tianjin 300457, China)
  • Online:2026-01-25 Published:2026-02-05

摘要: 乳清蛋白是乳制品中的一种重要蛋白质,含有丰富的氨基酸和生物活性肽,具有较高的营养价值。然而,乳清蛋白热稳定性差,在高温、高浓度条件下易发生蛋白变性、沉淀和氧化等问题,限制了其在功能食品、保健食品、特医食品等领域的应用。因此,提高乳清蛋白热稳定性的研究变得尤为重要。本文综述了近年来物理、化学和生物方法改性技术,以及分子伴侣在乳清蛋白热稳定性改性中的应用,并总结了用于评价其热稳定性与变性聚集程度的关键指标,探讨了改性后热稳定性乳清蛋白在食品、药品等领域的潜在应用价值和发展前景。

关键词: 乳清蛋白;热稳定性;改性技术;热稳定性评价指标

Abstract: Whey protein (WP), an important protein in dairy products, is rich in amino acids and bioactive peptides, and possesses high nutritional value. However, its poor thermal stability leads to issues such as protein denaturation, precipitation, and oxidation under high-temperature and high-concentration conditions, which limit its application in functional foods, dietary supplements, foods for special medical purpose, and other related fields. Therefore, enhancing the thermal stability of WP has become particularly important. This paper reviews recent advances in physical, chemical, and biological modification techniques, as well as the application of molecular chaperones in improving the thermal stability of WP, and summarizes the key indicators to evaluate its thermal stability and degree of denaturation and aggregation. It also discusses the potential application value and development prospects of thermally stabilized WP in food, pharmaceutical, and other industries.

Key words: whey protein; thermal stability; modification technologies; thermal stability indices

中图分类号: