食品科学 ›› 2005, Vol. 26 ›› Issue (11): 237-241.

• 营养卫生 • 上一篇    下一篇

藤茶辅助降血脂作用的研究

 刘翠娥, 王海玉, 王亚东, 张杰   

  1. 河南省疾病预防控制中心
  • 出版日期:2005-11-15 发布日期:2011-10-01

Study on Ampelsis grossedentata to Lower Plasma Lipids Level

 LIU  Cui-E, WANG  Hai-Yu, WANG  Ya-Dong, ZHANG  Jie   

  1. Henan Provincial Center for Disease Control and Prevention
  • Online:2005-11-15 Published:2011-10-01

摘要: 目的:本文主要研究大别山产藤茶的辅助降血脂作用,为开发防治高血脂的保健食品提供科学依据。研究方法:即用高脂饲料喂养动物形成脂代谢紊乱,再给予动物藤茶提取物经口灌胃30d,随机选择100名志愿受试者,每天按9g泡饮45d后,检测动物和人血清中TC、TG、HDL-C三项指标,动物试验结果表明:高剂量组总胆固醇含量下降明显,中、高剂量组总胆固醇含量下降幅度分别为16.7%、23.1%。低、中、高剂量组甘油三酯含量下降明显,低、中、高剂量组甘油三酯含量下降幅度分别为17.4%、17.8%、19.1%。低、中、高剂量组高密度脂蛋白胆固醇含量升高明显,低、中、高剂量组平均升高值为4.64、5.03、4.26mg/dl。人体试食试验结果表明:试验组降总胆固醇有效率为42%、降甘油三脂有效率为72%、降血脂有效率为28%,受试者血清总胆固醇、甘油三脂明显降低。结论:藤茶具有辅助降血脂作用。

关键词: 藤茶(显齿蛇葡萄), 降血脂作用, 高脂血症, 总黄酮, 双氢杨梅素

Abstract: Objective: To study the effect of Ampelsis grossedentata on lowering plasma lipids level. Methods: The hyperlipemia rats were fed with Ampelsis grossedentata on three different dosages respectively everyday. After 30d, the levels of TC,TG and HDL-C were assayed.100 patients with primary hyperlipidemia were randomly allocated into two groups, one treated group and the other control group. Patients in the treated group were given 9g/d of Ampelsis grossedentata. After 45d, the level of TC,TG and HDL-C were assayed. Results: the TC and TG level of rats could be lowered, the HDL-C level of rats could be increased. Whereas the effective rate of the patients treated group on reducing levels of TC, TG and plasma lipids were respectively 42%, 72% and 28%.Conclusion: In the study, Ampelsis grossedentata could lower the plasma lipids level.

Key words: Ampelsis grossedentata, antilipemic, hyperlipidemia, total flavonoids, dihydromyricetin