食品科学

• 基础研究 • 上一篇    下一篇

脱氢醋酸钠对断奶仔猪抗氧化能力的影响

屈长波,王 恬   

  1. 南京农业大学动物科技学院,江苏 南京 210095
  • 出版日期:2014-06-15 发布日期:2014-07-03

Effects of Sodium Dehydroacetate on Antioxidant Capacity in Weaned Piglets

QU Chang-bo, WANG Tian   

  1. College of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, China
  • Online:2014-06-15 Published:2014-07-03

摘要:

研究食品添加剂脱氢醋酸钠对动物抗氧化能力的影响。以仔猪作为实验动物模型,选用10 日龄哺乳仔猪(杜×长×大)192 头,随机分成4 组(每组4 个重复,每重复12 头),饲喂不含脱氢醋酸钠的基础日粮(对照组)、基础日粮中分别添加脱氢醋酸钠0.02%(实验组Ⅰ)、0.1%(实验组Ⅱ)和0.2%(实验组Ⅲ)的日粮,实验期42 d。结果表明:与对照组相比,1)仔猪51 d体质量,Ⅲ组显著降低13.26%(P<0.05),Ⅰ、Ⅱ组无显著差异(P>0.05);2)Ⅲ组仔猪血清超氧化物歧化酶(superoxide dismutase,SOD)活力极显著降低(P<0.01),总抗氧化能力(total antioxidant capacity,T-AOC)显著降低(P<0.05),而Ⅰ、Ⅱ组仔猪血清抗氧化指标均无显著差异(P>0.05);3)仔猪肝脏丙二醛(malondialdehyde,MDA)含量,除Ⅲ组外,Ⅰ(P<0.01)、Ⅱ(P<0.05)组均有明显升高。因此,日粮中添加0.2%脱氢醋酸钠,明显降低仔猪的抗氧化能力,食品中使用高剂量脱氢醋酸钠存在一定的健康风险。

关键词: 脱氢醋酸钠, 断奶仔猪, 抗氧化能力

Abstract:

The effects of sodium dehydroacetate on antioxidant capacity in weaned piglets were investigated. A total of 192
crossbreds (Duroc × Landrace × Yorkshire) piglets at 10 days of age were randomly divided into 4 groups with 4 replicates
consisting of 12 animals each. They were weaned and fed with basal diet (control group), basal diet supplemented with
0.02% (group Ⅰ), 0.1% (group Ⅱ) and 0.2% (group Ⅲ) sodium dehydroacetate, respectively. The experiment lasted for 42
days. The results showed that when comparing with the control group: 1) the weight of the 51-day-old piglets in group Ⅲ
was significantly decreased by 13.26% (P < 0.05), while groups Ⅰ and Ⅱ had no significant difference (P > 0.05); 2)
the serum total superoxide dismutate (T-SOD) in group Ⅲ was decreased highly significantly (P < 0.01), in addition to a
significant reduction in serum total antioxidant capacity (T-AOC) (P > 0.05). But the serum antioxidant indices in groups Ⅰ
and Ⅱ had no significant difference; and 3) the liver malondialdehyde (MDA) contents in groups I (P < 0.01) and Ⅱ
(P < 0.05) but not in group Ⅲ were increased significantly. These results indicate that the diet containing 0.2% sodium
dehydroacetate could significantly decrease the TAC in piglets. Thus some potential health risks may be caused by using
high levels of sodium dehydroacetate in food.

Key words: sodium dehydroacetate, weaned piglets, antioxidant capacity