食品科学 ›› 2010, Vol. 31 ›› Issue (17): 64-67.doi: 10.7506/spkx1002-6630-201017015

• 基础研究 • 上一篇    下一篇

豆豉水提物对α-葡萄糖苷酶体外抑制活性影响

陈 静1,李里特2   

  1. 1.北京物资学院物流学院 2.中国农业大学食品科学与营养工程学院
  • 收稿日期:2010-01-08 出版日期:2010-09-15 发布日期:2010-12-29
  • 通讯作者: 陈静 E-mail:chenjingsusan@126.com

in vitro Inhibitory Effect of Water Extract from Douchi on Alpha-glucosidase Activity

CHEN Jing1,LI Li-te2   

  1. 1. Logistics School, Beijing Wuzi University, Beijing 101149, China;
    2. College of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083, China
  • Received:2010-01-08 Online:2010-09-15 Published:2010-12-29
  • Contact: CHEN Jing E-mail:chenjingsusan@126.com

摘要:

本研究收集全国各地的37 种豆豉样品,测试其水提物对α- 葡萄糖苷酶体外抑制活性。结果表明:37种来源不同的豆豉样品水提物均对小鼠肠道内的α- 葡萄糖苷酶呈现一定程度的抑制活性,其中5#(L.Y)、16#(W.N.H)以及21#(M.W)豆豉水提物对α- 葡萄糖苷酶呈现较高的抑制活性(P < 0.05);此外,通过对高活性豆豉的蔗糖和葡萄糖含量检测,结果表明,尽管豆豉中含有微量的葡萄糖,但抑制干扰作用甚微。本研究结果预示着豆豉中存在可以强烈抑制α- 葡萄糖苷酶的活性成分,这种活性成分呈现较好的水溶性,可能是具有类似糖结构的成分在起作用,有待于深入研究。

关键词: 豆豉, 腐乳, α-葡萄糖苷酶抑制, 活性成分

Abstract:

Thirty-seven Douchi samples collected from various regions of China were tested for the inhibitory effects of their water extracts on alpha-glucosidase in vitro. The water extracts from all these Douchi samples could inhibit mouse intestinal alpha-glucosidase to a certainty extent. In addition, samples NO.5 (L.Y), NO.16 (W.N.H) and NO.21 (M.W) showed stronger inhibitory effect against the enzyme (P < 0.05). Moreover, microamounts of glucose existing in Douchi samples had less interrupting effect on the anti-hyperglycemic activity of Douchi water extract. This study suggests that there are some active components in Douchi, which can strongly inhibit alpha-glucosidase and present excellent water solubility. These components may have sacchride-like structures. However, this needs to be deeply investigated.

Key words: Douchi, water extract, alpha-glucosidase, active components

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