Polysaccharide Extract from Russula and Its Role of Lowering Blood Glucose and Lipid

doi:10.7506/spkx1002-6630-201009057

FOOD SCIENCE ›› 2010, Vol. 31 ›› Issue (9): 255-258.doi: 10.7506/spkx1002-6630-201009057

• Nutrition & Hygiene • Previous Articles Next Articles

Polysaccharide Extract from Russula and Its Role of Lowering Blood Glucose and Lipid

CHEN Xu-jian1，ZHANG Yuan-qi2

1. Yulin Normal College, Yulin 537000, China；2. The Second People s Hospital of Yulin, Yulin 537000, China

Received:2009-09-11 Online:2010-05-01 Published:2010-12-29
Contact: CHEN Xu-jian E-mail:ylcxj123@tom.com

Abstract

Abstract:

Objective: To explore the purification of Russula polysaccharide and its role of lowering glucose and lipid. Methods: Crude polysaccharide was extracted from Russula fruit bodies through soaking extraction method in hot water and purified through ion-exchange chromatography and gel chromatography. The mice model with diabetes and hyperlipidemia was established through the injection of alloxan and the feeding of high-fat food. The model mice were administrated with Russula polysaccharide. Blood glucose and blood lipid in model mice with diabetes and hyperlipidemia were evaluated. Results: GLU, TC, TG and LDL-C exhibited a significant decrease (P ＜0.01) in mice with the administration of Russula polysaccharide in a dose-dependent manner. Conclusion: Russula polysaccharide has excellent functions in lowering blood glucose and lipid levels.

Key words: Russula polysaccharide, blood glucose, blood lipid

CLC Number:

TQ929.2

CHEN Xu-jian1，ZHANG Yuan-qi2. Polysaccharide Extract from Russula and Its Role of Lowering Blood Glucose and Lipid[J]. FOOD SCIENCE, 2010, 31(9): 255-258.

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Polysaccharide Extract from Russula and Its Role of Lowering Blood Glucose and Lipid

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