A Preliminary Investigation into Canthaxanthin Accumulation in Male Rat Serum

doi:10.7506/spkx1002-6630-201205055

Abstract

Abstract: This study was aimed to investigate canthaxanthin accumulation in male rat serum. A total of 38 male SD rats were selected with 250 g body weight and divided into 6 groups of 6 ones each (the remaining two served as controls). A single (1 mL) dose of canthaxanthin (1.75 mg in soybean oils) was orally administered to each rat. At 0.5, 1, 2, 4, 8 h and 16 h post-administration, blood was collected from each group to analyze total flavonoids in serum by HPLC (equipped with C18 column and PDA detector). The results obtained showed that canthaxanthin was detectable in rat serum at 0.5 h post-administration, reached the maximum level at 2 h, and at 16 h presented a level lower than that at 0.5 h.

Key words: canthaxanthin, serum, accumulation, HPLC, male rat

CLC Number:

TS254.1

ZHAO Ting，HUI Bo-di， PEI Ling-peng. A Preliminary Investigation into Canthaxanthin Accumulation in Male Rat Serum[J]. FOOD SCIENCE, 2012, 33(5): 260-262.

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A Preliminary Investigation into Canthaxanthin Accumulation in Male Rat Serum

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